*Note: WBC title on the line for Canelo Alvarez only, after Cotto allegedly failed to pay a WBC sanctioning fee.
Miguel Cotto and Canelo Alvarez return to the Channel of Champions on Saturday in a mouth-watering clash that is the talk of our sport.
In this genuine superfight, the WBC title is now on the line for Canelo Alvarez only after the WBC stripped Miguel Cotto of his title.
BoxNation looks at six debating points surrounding what is perhaps the best match-up this year in boxing.
1) Are they ducking Gennady Golovkin?
GGG is the man to beat in the 160lb division and it seems likely that the winner of Cotto v Canelo will face the Kazakh KO machine after this weekend's Las Vegas humdinger.
2) Would they be tempted to meet Andy Lee or Billy Joe Saunders?
Andy Lee puts his WBO belt on the line against the Hatfield traveller next month in another middleweight classic being dished up on BoxNation.
Lee is already a name in America which would help, and promoter Frank Warren wouldn't be scared of pushing Saunders name forward it the call came.
3) Is there another incredible chapter to add in Cotto's career?
Cotto has been one of boxing's great titans of the modern era and competed at the highest level for well over a decade.
How high? Well 23 of his last 24 fights have been world title contests and he has won belts at super-lightweight, welterweight, super-welterweight and middleweight.
If he sees off his young and fiercely ambitious young challenger on Saturday it will cement his status as a modern great.
4) How damaging would a Canelo defeat be for Golden Boy Promotions?
Golden Boy have been brilliant for boxing, but have had it tough recently with fighters they built defecting to the PBC and defeats for stable stars Lucas Matthysse and David Lemieux.
If their biggest name suffered a second career defeat it would leave them some distance behind rivals like Top Rank and the PBC.
They do have some serious prospects and it might be a couple of year before they re-emerge as major players.
5) Can Canelo still become the next superstar of boxing?
Defeating Cotto will help his case and with millions of Mexican fans he is already Royalty in his homeland.
Even though he lost to Floyd Mayweather, his fighting style and accuracy mean there's hope he can become the sport's number one attraction over the next couple of years.
6) Can the fight live up to the hype?
Their fans certainly believe so. The Mandalay Bay Events Center showdown sold-out weeks ago, and there are close circuit screenings at several Las Vegas hotels.
Puerto Rico v Mexico rivalry is fierce and delivered classics like Salvador Sanchez v Wilfredo Gomez and Julio Cesar Chavez v Edwin Rosario.
Cotto v Canelo has every chance to be a fight fore the ages, and the only place for UK fans to see the fight of the year is on BoxNation.